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> it’ll definitely rank as the most costly and fatal mistake in the 21st Century

Ah, but the century is still young.

Very astute! The First! Lab escape happened in 2021. CRISPr was invented in 2000-2005ish. CRISPr cas9 around 2014.

BSL-4 labs have gone from 40 to 60ish in the last 25 years with another coming online almost every year.

BSL-3 labs are virtually uncountable and are in the 13000ish range in the USA alone (sorry, can't Remeber source)

Put it all together, and only an idiot STARTS with natural origin.

Also, there will be many many more.

So the only solution is to build my own BSL-4 lab and live inside it. We now have a "BSL-4 lab gap":

"We must not allow a mine-shaft gap!:

[I miss Peter Sellers!]