Author here. In 2007 when Django was starting to get popular there was a website called instantdjango.com where you could go and download a zip that would let you run Django and Python on Windows, with everything configured nicely.

I only used that version because it is the official one supported by cosmopolitan, but it is also possible to use newer versions with the same approach, for example Python 3.11 and Django 4: https://github.com/ahgamut/cpython/tree/cosmo-djngo (Website has been updated to point at that one).