I was put on Ozempic last year for a short amount of time. That, combined with changing of diet and starting an exercise routine, lead me to lose ~60 pounds in a relatively short amount of time (~8 months). I'm not taking the medication anymore and I did gain about 20 pounds back, but it's a lot easier going on a walk or run when you're carrying net 40 fewer pounds.
Willpower and discipline are simple things but they're not easy. In my opinion, it's important that the patient uses it as boost instead of a crutch and don't get too discouraged if/when they wean off and gain some weight back.