This is basically the plot of “white noise” with Adam driver (on netflix).
Summary: Chapter 21
Jack finds Heinrich on the roof, looking through a pair of binoculars at a distant black cloud of smoke. Heinrich informs Jack that a train car has been derailed. Later, they both return to watch the cloud. Heinrich says that the burning chemical in the air is Nyodene Derivative, or Nyodene D., a toxic substance that causes lumps in rats. The radio has already listed nausea, skin irritation, and sweaty palms as potential symptoms of exposure. Jack tries to reassure Heinrich that the smoke won’t come toward them and continues to act comfortable and indifferent. He sits down to pay the bills, even as rumors of increasing danger come in over the radio and phone. Sirens begin to blare through the neighborhood, but Jack declares that such things can’t happen in a town like theirs. New symptoms are reported on the radio, and the cloud is given a new name: the airborne toxic event. Heinrich tries to get his father to acknowledge the danger, but Jack declares that he is a college professor, not to mention the chair of a department, and can’t imagine someone like him fleeing something like an airborne toxic event. The family anxiously gathers for dinner as the air raid warnings grow closer.
https://www.wlwt.com/article/ohio-train-derailment-white-noi...