I'm a huge fan of it personally. To me, relative to Node the way this handles feels, broadly, closer to a browser -- by leaning on Web standards there's a variety of knowledge transfer between client-side work and server-side for things like packaging, API calls, and various other functionality; and it builds in enough basic tooling that I don't have to find or install or develop opinions on external libraries for handling anything from watching files to using environment variables to running tests (if I necessarily cared to do that with personal projects).
The limitations that stick out most to me personally are that there's still no ARM support, and that, while the Node compat is getting a lot better, it's still hard to get a clear sense of where it is for individual packages -- what runs natively/is isomorphic, vs what'll run under a compat layer, vs what just won't run at all.