I'm not so sure, at least I know plenty of people in tech hubs that are in a similar position. Certainly anything that reduces the number of jobs you can accept will limit your opportunities, but I'm not sure being open to in-office would immediately solve the problem.
In the end it doesn't matter. Due to family concerns relocation is not an option, and anything local would be a huge pay cut. I'll go that route if I reach the point where I need to, but I'm holding off for now.