Sure. Or it could just the kind of mistake that is being made all the time. I remember for example facebook taking itself offline[0], or cloudflare taking itself offline[1]. And of course pre-Musk twitter is well known itself to regularly have had significant incidents.
This new twitter incident could well be a result of layoffs and the resulting loss of institutional knowledge, but that's hardly a foregone conclusion.
[0] https://en.wikipedia.org/wiki/2021_Facebook_outage
[1] https://blog.cloudflare.com/cloudflare-outage-on-june-21-202...