Hypertrophy has largely been settled and the main mechanisms and science underneath are well known by now. Call is post-2017.
Source: up 40lb of Dexa scan muscle from 2014-2023, at 15lb greater body weight.
Not rocket science. Strongly recommend Renaissance Periodization (the hundred of hours of lectures on YouTube if that’s your thing, the two main textbooks, the training templates, the meal books, or the meal apps) as a potential vendor if you’re on the simultaneously on the brainier/geekier and more ambitious to reach intermediate or further side of humans.