Depends on what you put under "ergonomic", but you could take a look at the Ultimate Hacking keyboard: https://ultimatehackingkeyboard.com/ (split, ISO layout & mechanical switches, not wireless however).
I've seen this before, but at least in the order form pictures the ISO layout doesn't look any different from ANSI layout.
AFAIK, the only difference (for the UHK keyboard, at least) is that, on the ISO layout, the left-shift key is narrower, in order to make space for an extra key. This is visible for instance if you compare their US (ANSI) and UK (ISO) layout.
Maybe it is just me, but I don’t think a keyboard has ISO layout if it sticks with ANSI style enter - that pretty much is the defining feature