Electrical stimulation can boost brain's willingness to engage in mental effort
psypost.org
psypost.org
https://journals.plos.org/plosbiology/article?id=10.1371/jou...
The bigger question is what you want to use it for. I think we've got a ways to go before we have "fire-and-forget" procedure work for everybody. Depending on where/how/when you stimulate, it's sometimes possible to produce the exact opposite of your intended effect. One of the headsets marketed for improving gaming had a big dust-up over that.
Do you have any suggested introductory reading material for those interested in neuroscience? More detailed and technical than pop science-esq, without requiring subject matter expertise?
Are you interested in anything specific? Neuroscience is an absolutely massive field. At one end of my department, some folks are poking at the atomic structure of individual ion channels; at the other, people are looking at how social factors affect the brain and vice versa. It's hard to think of any one book that does it all justice.
On the other hand, there's been a flood of interesting books lately, so there's almost certainly something for you. Since you're on HN, you might like Grace Lindsay's Models of the Mind. It's about using math and physics to probe the brain, but it's a nice light read that focuses on analogies; no walls of impenetrable equations. If you like this, there are a ton of books that dive more deeply into the math to read next.
I've heard good things about Luiz Pessoa's The Entangled Brain, but haven't read it. It's more general neuroscience than focused on applications of math. People love Gyorgy Buzsaki's books Rhythms of the Brain and The Brain from Inside Out. I couldn't really get into them, in part because he was--loudly--wrong about the brain stim stuff in that article--but that's more of a personal beef.
If you want something more like a textbook, the standard is Kandel's Principles of Neural Science. It touches on almost everything, though often not in a particularly exciting or up-to-date way. It's not the worst book for a class, but it'd be a slog to power through in bed. Instead, I'd recommend Levitan and Kaczmarek's The Neuron: Cell and Molecular Biology. It covers a bit less (individual cells up through small neural networks), but I like the writing a lot more.
Another approach might be some hybrid science-biographies. These include Lessons from the Lobster, which is about Eve Marder and her work. The lobster stomach is a really fascinating circuit: seemingly simple, but capable of really complex behavior. The principles she worked out there have huge implications for more complex brains (like ours). Similarly, Brain and Visual Perception is about how David Hubel and Torsten Wiesel worked out some of the circuits in primary visual cortex--and won the Nobel Prize. I have not read Jill Bolte Taylor's My Stroke of Insight, but people seem to like it. It's about a brain anatomist realizing that she's having a stroke. Oliver Sacks' books are probably the standard bearer in this category. Some of the explanations are a bit dated, especially in The Man Who Mistook His Wife for a Hat (understandable, as it's from 1985), but the descriptions of the symptoms are fascinating.
Some anti-recommendations: I'd avoid Rodger Penrose's The Emperor's New Mind. It did get me interested in moving from CS to Neuro, but its explanations are, to put it EXTREMELY charitably, not very mainstream. Jeff Hawkin's book is not nearly as far out there, but his ideas also don't have a lot of traction. Stephen Grossberg's stuff is very polarizing: some ideas are very interesting, but also sometimes presented in ways that don't tie in well with the rest of the field, so I wouldn't start there.
That's a random walk through my reading list! If you're interested in a particular niche, let me know. There's also cool stuff about drugs, weird animals, sensation, etc...
There's more to do before it's a routine treatment, but there may be something there. Until recently, I think most people have been trying to enhance weak activity with stimulation, but some of our data suggest it's easier to break up pathological activity, which I think is the issue with tinnitus.
There is also a constant light vibration when you run your fingers lightly along the body. It's quite Shocking that this is apparently "normal". None of this happens when it's running on battery.
Either you get rid of that device or you buy something like this: https://www.google.com/search?q=apple+grounded+extention+cab...
I am pretty sure a bad switch mode power supply, can push out some nasty stuff.
The shocks you observe are caused by your body slightly grounding the conductive case. They are seen with any conductive case equipment used without grounding. Fortunately, they are not dangerous on doubly-insulated equipment like Macbooks.
https://www.apple.com/shop/product/MK122LL/A/power-adapter-e...
It can also, possibly intentionally, be used as a bottle opener.
I always assumed that was just because the surface has a strange microscopic pattern. I don't have one now, but I believe it only happens in one direction.
The power adapter extension cord has a ground pin, you can use the extension cord if you want to ground the computer.
The high frequency buzzing you feel in your hands as you place them on the computer when the incoming power is not a proper clean sinus wave is unpleasant. Stoping that buzzing would be a good reason to ground the adapter even if it not legally required.
I’ve used countless MacBooks over the years across several countries and even on square wave UPS systems. I’ve never experienced anything like this. This is literally the first time I’m hearing about this phenomenon.
The way people are talking about Apple products as having some sort of weird grounding defect in this thread is honestly kind of baffling, given that they obviously have built a product that complies with all international regulations around the world.
You have to purchase an extra cable with a grounding pin for your power adapter to ground a MacBook.
My prescribed medication (little orange footballs) regularly helps me overcome executive function inhibition, and I was hoping this tech could work as an alternative or supplement.
There’s a lot of friction in setting up a session, because in order to have proper electrical conductivity, these devices typically require you to add some contact pads soaked in salt water.
It becomes noticeably unpleasant for me after only a minute or two - a very particular hybrid sensation between heat and… tingling? Pinching?
Combined with salt water dripping down my face, the initial appeal faded quickly.
I’d like to try it again, but it’s been sitting in a drawer for years, so I wonder if the battery hasn’t degraded. I don’t think I’d like to replace any components on such a device…
Maybe that would make the experience a little better.
SignaGel is a conductive gel. It'll mostly stay in place and stays wet a lot longer than the sponges, but it is a little gross. Get it from a medical supplier rather than Amazon, where the individual tubes are massively overpriced. You might also be interested in 10-20 paste, which is a sticky conductive putty. It's a bit more expensive, but it stays put. Instead of the bands, you can also try a neoprene "swimcap" style holder.
Some of the tingling is unavoidable--the currents are driving fibers in the skin--but you can do a few things to reduce it. First, make sure there's good contact with the scalp: fully coat/saturate the electrodes and make sure they're pressed tight. The lower the impedance, the better. because the "dose" is specified in terms of current and you want to use as little voltage as possible to deliver that. Second, gradually ramp up the current instead of just switching it on/off. The sensation will diminish a bit over time anyway, so slowly increasing the current will make it more bearable. The difference between on/off and a 30 second ramp is really striking! We've used a topical anesthetic to block sensations, but it's a giant pain--it takes an hour to kick in and you need to tightly cover it too. Finally, be careful because you can burn the skin!
It doesn't directly have long term impacts, but I find reducing anxiety in the moment can build up memory for better mental practices in the future. I use it for a 40 minute session 2-3 times a week, especially if things are feeling really difficult when I might ordinarily need to take an anti anxiety med. The effects do last longer then the treatment duration, many hours afterwards for me. It can help me meditate as well, increasing my focus and reducing mental distractions a bit. If you turn it up too high, it starts to give you a dizzy/vertigo feeling, the recommendation is to run it just below that level.
Anyone else have experience with the Alpha-Stim or other CES/tDCS/tACS devices for mental health? I wish the nice research devices like in the study were available to the public, there are a ton of settings and modes they are able to test in studies like this, that you'd have to buy a dozen consumer devices of questionable quality to get any similar flexibility.
While my usage was occasional, I did have a very unique perceived response to a session, and it wasn’t dissimilar to stimulants prescribed for ADHD.
However, that response didn’t last much longer than a few minutes after removing the device. I also didn’t feel the mild pseudo-euphoria I commonly experience with ADHD medication, which seems a significant element of resolving ADHD symptoms.
This is more of a side effect, which disappears over time. Relying on the euphoria of stimulants to get work done is a dead end, so be careful with this assumption.
(I'm referring to the fact that it made us drop out of school and lose 3 jobs. It has, objectively, made our life absolute hell. And we thought we were just lazy or stupid for over a decade until we found out about ADHD. Stimulants don't help us.)
-Emily
I find that i feel the effects of my Vyvanse nearly all day, and it's only for the last few hours of the night that it fades. So though I do have to be a bit careful then to similarly restrict eating, if I can trick myself by like, brushing my teeth early or drinking a lot of water before it wears off, that can help with (though obviously not cure) the binge eating.
I use Brain.fm for focus and its great.
Clever idea but I really wonder the long term effects!
Brain activity consists of intricate patterns of electrical activity, created as neurons process and transmit information. tACS, the method used here, creates electric fields inside the head, which interacts with neurons’ own electrical activity. The effects are pretty subtle—-it can’t make a neuron spike on its own and thus release neurotransmitter. However, it can shift the timing of spikes caused by its “natural” activity”, and thus change those activity patterns.
(My group looks at this in animal and computational models, where we can measure this directly).
That's a super cool activity, sounds so simple to manipulate your brain into the 'productive' behavior.
The effects turn out to be pretty complicated because other ongoing brain activity shapes the stimulation effect (and vice versa). Sometimes, the same stimulation can even produce totally opposite effects.
Elsewhere in the thread, I linked to an article we wrote about this and other challenges for doing (useful) brain stimulation.