I think ML/AI will just blow past us. It's sort of like trying to be a computer engineer 30 years ago, or telecommunications engineer 20 years ago. If you're not there, you're too late.
There's still the application layer. Be an expert in a field and build something on top of the foundations that others set down.
I think big tech is a regretful place to be though. It depends entirely on what you would regret. Some regret not having kids. Some regret not doing more. Some regret doing too much and missing out on life.
I think some people just have a pioneering spirit that most won't understand. It really doesn't matter for humanity whether you invent the first smartphone or electric car or land on Mars. Someone else will do it. Often they do it months later, sometimes decades in the case of expensive things like space travel. You probably change the world more as a big tech engineer than a CEO of a multi-million dollar company.
Money is everywhere. It's easier to optimize for what you want to do that pays well, rather than what pays the most. Because what pays most often lands you with high living costs. Wealth attracts rats too.