My suggestion for you is to do the following: start
your CSS stylesheet with
html {
font-size: 62.5%;
}
NO, NO, AND NO! I set my font size to what it is for a reason. Web designers need to learn to deal with it. If you're manually tweaking font sizes, you're doing it wrong. Please, leave them at the default values; they're that way for a reason. I want a website that doesn't cause eye strain. Make sure your site scales, and things work without absolute pixel sizes.