> TiddlyWiki is an amazing piece of software, but it has too many points of friction. The first being that you have to run a local server, which eliminates 99% of users.

This was not always true. One reason TW became popular was because you could save your data without running a web server on Firefox. Then Firefox decided to pull that functionality, and TW suddenly became a lot less exciting. You could still download apps or use the Github saver, but those were far less appealing than the old approach with Firefox.