If money is important to you, do it. The sacrifices you'll generally make:
- you'll need to work on POCs (new products) in your off-time. Most of these companies don't schedule innovation.
- promotions are based on project delivery and impact within huge orgs, which makes it more hard.
- you'll probably run through a number of teams before you find one you like. Colleagues are generally good, management is lackluster, and execs are mostly poor. There are exceptions. I found a place where management and execs are great, but I'm not sold that this paradigm will endure.