Currently building with Next/TRPC/Prisma/PG and would choose it again. I might be a little slower than starting with a full-featured MVC kit like Laravel or Rails, but having an e2e type system is so worth it to me. I do miss having a more mature ORM.
I'm constantly tempted by Phoenix but desuaded by the lack of a type system. Does elixir somehow make up for the lack of types as a functional language? Also, I can reuse a good deal from my current stack in a react-native app for mobile, which I'd miss out on in another framework.
Wish I could say Flutter, but have not been impressed by the web experience.