As someone who lived through the .COM crash and implosion and then 2008, any company with "strong cash reserves" and "trajectory to profitability" is not making more money than they are spending. They are, to use the SV term - losing runway. This is catastrophic because it's infeasible to raise money right now to extend the runway. If the plane is not airborne (making significantly more money than they are consuming) by the end of the runway, they crash and burn, taking themselves and the company's investors with them.
My experience has been highly capitalized, but running way in the red are the worst possible place to hide when a significant economic event occurs. Confluent has raised capital 11 times (from a quick crunchbase article) and has a product that is open source core, giving its customers an escape path.
I'd also point out that this is a bit snowflake. The average annual corporate turnover rate is way higher then this number. If not for the immediacy of the headwinds, almost every company could handle this by simply not rehiring after attrition.