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What about twilight anesthesia? With my cardiac problem, I can't have general anesthetics, but I can have Fentanyl/Midazolam to sedate and numb up a bit. Saying "it's specific to fentanyl" doesn't help those for whom fentanyl is a life saving drug.

The reply above that the real issue is WHY Americans like fentanyl so much is on the money in my opinion.

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Well the idea is not for everyone to get OUD vaccines. They would be targeted to people with OUD. If you did have OUD, this treatment would unfortunately probably not work for you due to your cardiac problem. However, depending on the severity of OUD and how effective this vaccine turns out to be, it might be worth forgoing the possibility of surgery.

Forgoing surgery in my case would be rather fatal.

One catch is that if you're undiagnosed with some problem like mine (Brugada Syndrome) you might get the vaccine before you know that's a bad idea. I have, in the past, been dependent on opioids thanks to my broken body, and yeah, getting off them has challenges. But I think the key is WHY some people like them so much. There's something a bit off when the aim is to take so much you vomit but don't die, which I'm given to believe is the "ideal" recreational dose.

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