Something like one third of the full-time employed population of the UK took an antidepressant during 2021-22.

I don't know if that's indicative of anything. How could we compare that to people living in the same area, say, 100 years ago. If they had access to antidepressants would they seek that class of drug?

Could we use alcohol / opium / marijuana consumption as proxies, rate of some sorts of crime, infant mortality?