For me personally it took 2 months to "fully" adjust (meaning I can type without looking at the keyboard but every now and then I make a typo and need to correct it). I used this -> https://www.keybr.com/ almost every day. You can just set preferred layout without actually changing your keyboard's settings and it have very nice "teaching" sessions.
Tbh I don't notice a huge difference, its more comfortable but sometimes I have a brain lag when I need to type on my phone since its on qwerty. Ergo layouts tends to be worse on mobile (because ergo usually have common letters close to each other and its not very cool on a small screen, qwerty is suprisingly one o f the best for smartphone's 2 thumb style)