Is this really a mystery still? Well we know we can't blame it on fats anymore, our governments have tried that completely failed trope for 70 years now. And looks where it's gotten us. Heart disease is killing western diet eaters like there's really no tomorrow. I think it's obvious that constantly high insulin is the biggest driver of vascular disease. Hyperinsulinemia precedes diabetes and is measurable 10-20 years before your a1c will detect pre diabetes. This drives virtually all diseases of "modern western man/person" - heart attacks, stroke, dementia, connective tissue diseases, diabetes. It's insulin!

Low fat diets high in refined carbs disrupting the absorption of k, d, e, a. sugary beverages with zero fiber, 3 meals and 5 snacks a day so your insulin levels never come down even at night sometimes. Your body can never repair itself or stop storing fat instead of using them. 3 meals and 5 snacks a day= zero ability to distinguish cravings and real hunger. Being told to gobble 5+ fruits a day by every dietician. Fruits bear in the winter, we live in climate controlled buildings. Why are we gobbling so much fructose from 5+ fruits a day.