Early adulthood is when mental illness often sets in, especially illness like Schizophrenia. You're implying cause one way without considering the other likely alternatives:
1) Your acquaintance started smoking a lot of pot because of the onset of early schizophrenia symptoms as a coping mechanism.
2) They are unrelated and early adulthood is just when people experiment more with drugs, and also when conditions like Schizophrenia start to manifest.
> A second cousin became mentally retarded immediately after smoking a joint. He's now a 30 year old who can't tie his own shoes.
I don't know what to say to this other than nobody's ever established an even remotely plausible link between these two things, assuming you aren't being hyperbolic.