> Another reason might be domain trust? If spammers use omg.lol subdomains the entire thing might be blacklisted for email.
I think that them being on the https://wiki.mozilla.org/Public_Suffix_List makes that unlikely. (a Public Suffix is a thing like .co.uk — would it make sense to blacklist .co.uk? Not unless you're the type of postmaster who is willing to blacklist entire TLDs like .biz as well.)