Package local nicknames. The situation that libraries like Alexandria are in is really sad.
Nested namespacing/packages.
The ability to alias imports, like in Python.
In the same vein, most symbols in the spec should be moved into a standard library.
A general equality predicate which can be specialized by the user.
Just replace multiple-value-returns with structs, they don't add anything useful.
Standardize some variant of arrow macros.
Every form which introduces a binding should be able to take a (optional) type specifier. It'd be great if compilers could use this option to remove generic dispatch in certain compilation modes.