For those that haven't done mushrooms, there's different types of mushrooms. They all have different effects, some stronger than others. Tripsafe.org has some really good information on mushrooms and LSD with respect to the experiences users can expect to encounter.
My personal use of mushrooms, which isn't always medicinal doses, has been productive. Mostly, I have fun, do things I already love doing, and can be a bit more social. Mushrooms end with an "afterglow" that is a bit like being on an antidepressant for a while, but this depends per strain in my experience.
They're definitely good for addressing trauma and I'd agree with the neuroplasticity claims. I won't claim they've "changed my life" mainly because hallucinogens will only change what you really seek and work to change. In my personal opinion they just kind of grease the wheels for change.