Solutions are seldom the result of one lonely working geniuses.
For instance the internet or FB changed the world, but I wouldn't categorize their inventors as those crazy ones mentioned in the article.
We just tend to attribute special features to the most well known people, higher endurance, greater skill, stronger will.
There are way to many inventions and companies to thinks the world is formed by a few 'crazy' ones.
The only crazy one who achieved that are the real crazy ones and they didn't change the world to the better, see Putin.
Even that was a team effort and I doubt that people like Sabin count as that kind of crazy mentioned in the article.
Those are average scientists, not meant pejoratively, on the contrary, doing their job and sometimes the results have a big impact.