In art school I took a lot of large format photos of industrial facilities at night, which often involved climbing chain-link fences with a huge pelican case and tripod. Totally worth it for the end results, and looking like a quaint old timey photographer was helpful the few times I was confronted by security guards. :)

I've got two large format cameras.

One is a Horseman L45 which is a monstrosity that has a rail. It can only be used on my largest of heads (a bogen 3047 head).

My other large format camera is a Horseman HD field camera.

While the L45 is a beautiful camera, it is, by itself, a 10 lb camera that can only really be carried in a suitcase sized hard case that supports the rail properly. (Not my camera - but it gives you an idea - https://www.ebay.com/itm/364081119414 ).

The HD field camera is the one I'd take lug around in a slightly oversized messenger bag. http://www.bnphoto.org/bnphoto/LFN/CamProf_Horseman1.htm

The front standard of the HD had some reasonable movements. There was also a FA ("fine art" rather than "heavy duty") one that had a little bit of rear standard movement but was a bit heavier and less rugged.

My favorite use for the HD camera was doing a in field polaroid transfer onto a watercolor paper postcard which then got a stamp on it and went into a mailbox or giving it to a person who was interested in it as I took the photograph. These were necessarily a one of a kind image as the process was destructive to the polaroid. I might still have one in a book of watercolor paper as I was working on learning the process at Fort Point (hallway, 2nd floor, south side of the building, shooting west) as that was a place that was often quiet enough to photograph without disturbance and the staff was amenable to a photographer with a tripod.

Some are really portable - I used to travel with a crown graphic, which folds down small and light. You can do tilt shift with - it’s only in one axis but that’s plenty, as the camera is light enough you can rotate it.

The heavy bit was all the dark slides and film.

In all seriousness, I recommend lifting weights. Once I discovered how much an 8x10 field camera, accessories, and a suitable tripod weighed, I realized I'd only be able to schlep it around if I started building muscle mass.

I switched from APS-C to MFT because it was too bulky. These days the camera stays at home often.

Louis Mendes will disagree with that: https://www.youtube.com/watch?v=x8KOAj6Caf4

:D