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I am a current LispWorks customer using the product for new product development. I wouldn’t consider my usage niche, but then again, I am not sure what you may consider to be niche or not.

I did some work for a machine translation business that used Common Lisp as their "secret sauce". As they considered it a serious competitive advantage, you wouldn't hear about it anywhere.

I've seen this with quite a few other companies since, but that means that lots of companies could be using lisp and nobody would ever know about it.

Some years ago I read the same "secret weapon" rhetoric on a website dedicated to ... Cobol; I've not taken it seriously since.

A few days ago I noticed that commercial Smalltalk also still exists:

https://www.cincom.com/us/smalltalk

By niche, I assume you mean niche interest rather than niche purpose. They're both general-purpose languages that are usable on the latest OSes, after all.

Isn't grammarly using lisp?

One of the biggest workloads on Google's Borg is the one running the flight-scheduling service that run on CL.