No Agenda with Adam Curry and John C Dvorak. 6 hours a week of media deconstruction
I just finished #1500 and I'm probably going to be all caught up in the coming weeks what with holiday travel and all but yeah if anyone else wants to listen to NA but is overwhelmed with the amount of content they put out each week, I can't recommend listening a few months behind enough, for the additional dimension of interesting perspective it gives.
also, unrelated, but Hoteps BEEN Told You is another great listen, however most here will find it to be quite the acquired taste. (disclaimer: I made a website for them.)