But... actual guidance as to how to use it there is still pretty thin on the ground!
Short version: use WAL mode (which is not the default). Only send writes from a single process (maybe via a queue). Run your own load tests before you go live. Don't use it if you're going to want to horizontally scale to handle more than 1,000 requests/second or so (though vertically scaling will probably work really well).
I'd love to see more useful written material about this. I hope to provide more myself at some point.
Here are some notes I wrote a few months ago: https://simonwillison.net/2022/Oct/23/datasette-gunicorn/