You've cited D3 but I notice that you haven't mentioned Observable's Plot[0], a Javascript GoG that wraps D3. They're both Mike Bostock libraries, so Plot is the pseudo-"blessed" D3 high-level abstraction layer.
I've shied away from Observable, I didn't quite like the lock-in to their notepad-like env, and all the examples following what to me felt like a backward style. It's great to see they've produced a higher-level complement to d3.
But the lock-in is less severe these days. The parser, runtime and standard lib are all open-source, so you can run a full notebook in VSCode https://marketplace.visualstudio.com/items?itemName=GordonSm...
I've come to appreciate the non-standard extensions they've made to JS too - the reactive cell model has greatly reduced the amount of code I've needed to write compared to a hypothetical React equivalent. It's my #1 platform for my small side projects these days.
I'll quickly note for anyone uncertain - Plot is pure JS so it doesn't have to be used in an Observable notebook. Will run anywhere D3 does.