I've driven truck for 4+ years.
Side mirrors: I have _never_ cleaned the mirrors by hand. That happens when I'm refueling with a squeegee on a long pole that they have at truck-stops. I will tell you that those mirrors will vibrate like hell and be difficult to see clearly out of. That far away from the chassis and with only one point of contact will make it vibrate a lot.
Gatehouses: that is a very valid point, but most guardhouses (I mostly just have experience with Ford/Chrysler/GM) make you get out of the truck and go open up the trailer. You don't even roll-down the window to talk to them.
Weigh-Scales (aka Chicken-Coops) where Highway weight inspection happens: Most just use a speaker on a pole at window height, but other places (like USA/CAN border crossing) you have to pass paperwork back & forth to agent, so this would be difficult.
Entry/Egress: these are valid points but the need to enter/exit from the passenger side has only happened to me once. My biggest use of the passenger seat: That's where I kept my cooler for food/beverages.
And that brings me to my list of observations that make this tractor seem like a non-starter (from things i noticed watching the '10 hour drive' video):
(1) The monitor on the right-side of the driver. Some of the time it was a map/GPS, but most of the time it was displaying text that the driver leaned over/turned his head to read. This might have been dispatch notes, or vehicle diagnostics or something else. HELL NO, not even once would I ever drive something that required that much attention away from the road.
(2) Food/Beverage options. Most drivers that I ever saw used a LARGE 24oz-36oz insulated mugs for coffee. A lot would pour an entire pot of coffee into their mug! So most trucks had 'over-sized' cup holders. The 'nicer' trucks I drove also had shelves with guard rails (it always reminded me of boat-storage) in areas that I could put food that I could eat while driving. I didn't see that same kind of space. The less-nice trucks would force me to use the passenger seat. This truck did have lots of area, but there was nothing to prevent things from sliding around.
(3) Load/Log paperwork: Usually kept in a clip-board (mandated by law if carrying hazmat material to be stored in drivers-side door pocket). Once again door placement and lack of shelves play an issue here. I often kept mine on the passenger seat. This material is rarely touched while driving, but there is a considerable amount of paperwork that needs to be done each time the truck stops. Related: Notepads. About half the companies that I worked for required that I log the vehicle mileage (and time) when crossing state lines. There might be adequate space for this. Notes were needed to be written down quite frequently.
(3) Range to refuel ratio.
I drove a 600 mile radius centered around Detroit. I would goto Quebec, Missouri, Tennessee, and all points in between. Each time I needed to 'fill' the fuel tanks would take ~30 minutes. That 30-minutes would give me ~1800 miles of range (VERY rough estimate, I never got close to empty). I would often get fuel at either designated locations (like at the company lot)or when I was OTR I would do it before I stopped for the night (as needed). Even if Tesla built out a super-charger like network for the trucks I can't imagine having enough time to make 3x more stops, with each stop taking MUCH longer.