It’s the story of Emil Freireich, M.D[0] who went against conventional wisdom at the time in treating childhood leukemia and (as I recall) made what was once a almost guaranteed death sentence for children something with higher survival rates and ultimately saved millions of lives, but his approach, as told in the book, was not for the faint of heart and it’s credited to his tumultuous upbringing that made him hardened to criticism that would deter others from pursuing something they had conviction about, basically.

At the time Emil was (as I recall) treated as an outsider and viewed with skepticism for his work until basically it was irrational not to see how he was saving lives

[0]: https://uofuhealth.utah.edu/innovation/news/2014/07/malcolm-...