I flew on the second floor of a 747. It felt posh for some reason. Also the flight was super smooth. I suppose its weight and sheer size helps with that.
https://www.seatguru.com/airlines/Lufthansa/Lufthansa_Boeing...
In the early-mid 2010s I was fortunate to fly several times on the upper deck of an EVA Air 747 (SEA–TPE). On these planes, the upper deck was regular economy in a 3x3 configuration. It felt like a miniature 737 inside the huge 747, cozy in its own strange way. They also provided slippers and the window seats had a fun shelf/storage space, making it feel all the more special.
Also the storage bins along the walls due to the sharp angle were awesome if you had a window seat.