I welcome these changes... Yes we'll need to rethink our urbanism, but if anything this switch feels like a coming back of what our urban centers are supposed to provide us.
Imagine parking spaces becoming local artisans/food stalls, conference rooms becoming event spaces, coworking spaces adapted to people's lifestyle and living patterns (e.g. a suburban cowork with childcare and a dog park).
"gutting downtown" might be true for those who are wary their office real estate investment will not have a positive ROI. But the way I see it, this change in urban patterns is a paradigm shift in wealth distribution patterns and in economic opportunities for leisure services, both locally and globally.