Do you happen to have a mobile phone with AT&T and are near Fremont, CA?
sudo lsof -n -i :4500
Wi-Fi can work the same way, though it sometimes requires an extra step to place your machine's network card into "promiscuous mode" in order to see traffic neither to or from your machine.
There's examples of WiFi calling causing this type of issue, described as a packet storm. For example, here's a reddit post with similar symptoms you're describing. https://www.reddit.com/r/networking/comments/3g31mc/iphone_w...