With Alfred and a well-tuned Quicksilver, I can:
* hotkey it open
* punch in the minimum to identify the application I want (usually 1 or 2 keys, 3 for rarely-used ones)
* hit enter
and be done with it in well below 1/2 of a second.With Spotlight, I can:
* hotkey it open
* punch in the minimum to identify the application (over 2x more, almost all the time)
* wait for it to update
* it shows the wrong application / the last movie I played and finally displays the 3rd+ letters I typed
* wait for it to update again
* double-checking that it's the right application (it frequently isn't)
* hit enter
* hope it doesn't update *again*, causing me to launch the wrong application
the whole process typically taking >2 seconds nearly all the time, sometimes 5+ if it's a less-used application.Quicksilver in particular has a nice 'open with...' method which gives you a couple keystrokes to pick the file, 'ow<tab>' to open with, and a couple keystrokes to open it in the application of choice, all generally in less than a second. Alfred might have something similar in the PowerPack (paid), but I haven't purchased it.