A true UNIX is hard to beat. I grew up with macOS and was devastated when my Mac broke & couldn't afford a new one. Been despising Windows for the past ~1.5 years. OpenBSD is nothing like macOS, but it is still UNIX.
Doesn't Nvidia make first-party drivers for OpenBSD? And they're more likely to work since "OpenBSD" is far more specific than "Linux"?
I think KISS Linux is my favorite in terms of control, but it gives me so much control that I was never able to get it working. Its build system is theoretically awesome, but in practice maintaining my own distribution is less fun than it sounds.
Alpine is my favorite in terms of runtime stability since it essentially reimages itself into a tmpfs every boot and packages are completely atomic. But the fact that everything is statically linked means it's a pain to get anything working, and I haven't yet found anything that fills both niches. (I have not tried Silverblue or NixOS yet)
Arch is my favorite in terms of customization because basically everything has an AUR package these days, including the old traditional window managers (i.e. blackbox) that make for a utilitarian UNIX, my favorite kind. (With Wayland that all goes away, which is why I despise Wayland.)
Ubuntu is far too "stable" for my needs, and I commonly find that the newest release is already years out of date on packages. You basically need Linuxbrew to do any sort of bleeding-edge development on an Ubuntu machine.
I'm open to trying more, of course.