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Sure, many namespace collisions for D2 exit in the universe of possible meanings for the acronym, but in a computer context, and whose headline is “now open source”, it’s reasonable, expected even perhaps, to assume Diablo 2.

Also, and I may be showing my age here, who refers to Destiny 2 as D2 without any context?

Programming language D 2.0

Not my fault they chose a non unique name for their project. I just pointed it out.

Supposedly naming things is one of the problems in programming.