if __name__ == "__main__":
For example, I think if you'd have to explain how to change the string representation of some kind of object, saying "just define the 'str' method and then call it, like 'something.str()'" is simpler than "define a '__str__' method -- don't worry about all the underscores -- but then don't call it directly; instead of that, use the global 'str' function".
I don't know if that extra indirection (i.e. calling 'str', which, in turn, calls '__str__'; or 'next', that calls '__next__' in Python 3) adds more value than the simplicity of not having that extra indirection in the first place.
Just about the only underscore that you can't really avoid is the constructor syntax, "def __init__()". Which I guess is tolerable.
Can you elaborate on that point? I thought that was the canonical way to do exactly that... http://docs.python.org/library/__main__.html. If there's an easier/less verbose method (pun not intended) I'd love to know about it.
It is this environment in which the idiomatic “conditional script” stanza causes a script to run
The conditional script stanza is optional, and intended to make a .py file function as both a script and a module (i.e. be importable). To me, it's unclear why you would want to do that. The only thing you have to do to avoid using __main__ is not require any file to be both a script and a module/library. Then just put any entry-point code at the top level of whatever script invokes your program. Unfortunately the __main__ stanza is pretty widely used though.
On the topic of modules, there is a wrinkle in requiring __init__.py to be present in any library subdirectory that you want to be part of the namespace. It would be nice to have a more intuitive way for that.
I especially love it when I'm first coding, cause I like to test as I go. That allows me to run it to see what works and what doesn't.
When I'm finished, I know that I can just plop that file into a directory and use it as a library afterward. The majority of the code that I write implements that, and I find it a godsend, personally.