I use https://tweetdeck.twitter.com/ with an adblocker and never see ads.
(example: polls have never been ported to tweetdeck)
I don't think tweetdeck has seen active maintenance in years.
Prior to the Tweetdeck URL, I used the OSX client which I also really liked, mostly for the ability to just copy and paste an image straight into a tweet. So functionality wise, I feel like my experience has actually declined since then.