Not from a technical standpoint, but from building a userbase.
The X-factor for Twitter, from my observations, was that they used established media as their biggest advert or ambassadors. This was kind-of organic, though making tweets easy to embed was surely one of the biggest part of it. The value of the free advertising Twitter has received from publicity in media is probably in the hundreds of billions. That's all from making it easy to embed tweets in articles, providing APIs and branding guidance for on-air graphics and so on. They quickly got journalists and news producers as users. The snake eats it tail and as soon as politicians noticed that a tweet could be on all the news outlets within the hour they focused more and more of their messaging to be through Twitter. That's really hard to build up again.
And on that same note the media can kill Twitter in a few weeks, stop saying X said Y on Twitter and just say 'on social media'. Stop embedding tweets or using screenshots/branded graphics from Twitter - or just stop reporting what someone has posted on Twitter.