Making the statistically best choice is still the best choice even if you get an undesired outcome.

Good poker players can lose all their chips at the table to an unlucky draw and walk away knowing that they made the right play and that they'd do it again, even if they got unlucky on the river card. Good basketball coaches will still draw up plays to get the ball into the hands of their best shooter at the end of the game even if they miss sometimes.

If you're choosing between option A that has a 0.0001% chance of hurting you and option B that has a 10% chance of hurting you, and you choose A and still get hurt, that doesn't mean you made the wrong choice or that if you have it to do over again you should choose B.