You have $100 worth of stock in Google. You think Google stock is going to appreciate so you borrow $50 of my money to buy more stock. I see that you have $100 worth of Google stock which provides me with some security that you have a valuable asset and are a worthwhile borrower.
But, instead of Google's stock value increasing it starts to fall. You took my money and I'm getting nervous so I force you to sell your Google stock. At one point you had $150 worth of Google stock but now I've forced you to sell your stock for a total of $75 which allows me to recoup my lent money ($50) plus my fees and I really don't care how much money you are left with, if any.
This is important for the economy because credit (which this is) helps create growth and drives economies - when credit is tight then economies grow slowly if at all.