As a parent who doesn't enjoy young children, honestly being able to jump in at the less physically demanding ages (like 5+) sounds like a dream, if somehow it can be navigated while still paying top people to take care of them (her family can) and have them not hate you. For the first couple years with a kid I thought about how prison would have had a lot more freedom than parenthood, and yes I've been locked in a cell before (although not for years). If you get tossed in a cell with chill people it's honestly way more peaceful than a baby/toddler.
If Holmes actually wanted kids IMO it does seem like the stars align for her to do it now while the sociopathic upsides are at their maximum. There's a decent chance the baby will be shrieking in someone's face while she peacefully sleeps in minimum security bunk. She likely won't experience the tantrums, the worst of the sleepless nights, changing diapers, potty training, the worst years of illness and communicable disease, and when she emerges her children will be semi-rational beings capable of logic and physically durable and possibly even independent enough to be left alone briefly while she goes on a trip to the store or a run.