When I was looking for a job I got some of those autoreplies, and IMO, they are worth nothing. I already got confirmation that the form (in some giant enterprisey applicant tracking system) was submitted, sending me an email does nothing for me. If you would let me know when a human sees my resume, that would perhaps be meaningful, but there's no way they'd go for that level of transparency.
I love getting auto-replies because a lot of times the application process is to send an e-mail to jobs@example.com. Getting a reply that your resume arrived intact is always reassuring.