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Most modern architectures are better than waifu2x, this includes real-ESRGAN trained on the anime dataset, SwinIR.

I'll give it a go, but I've tried several and waifu2x gave significantly better results, so I'm not expecting much will be happy to be wrong!

My use case is 2x upscaling detailed, very small pixel-art-style images, like icons and retro game assets.