What do you have? (Crossing my fingers you don't say Razor)
Not the person you asked from but I have the SteelSeries Aerox 9 (wireless). I play MMOs on the regular and dabble in power-user land and 3D-modeling w shortcuts.
I'm using a Logitech G604 at work, I have 15 buttons of keyboard shortcuts on it.
I love this mouse. Logitech software could be better, but it's much better than Razer's. Synapse seems to ruin what would otherwise be great hardware for the money.