"There is one person in charge of every office in America, and that person is Charles Darwin..."
"You don’t call retarded people retards. It’s bad taste. You call your friends retards when they are acting retarded."
Is it worse to have some condition of your birth used as a casual insult -- a reminder of your misfortune? Or is it worse to be constantly patronized, often behind your back by throngs offended on your behalf?
The answer depends on your culture and outlook on life I suppose.