By internet standards. We're 2 or more orders of magnitude smaller than the marquee names. My guess (which I don't want to find out by experience) is that the pressure scales non-linearly, so a hundred times the users would mean who-knows-how-many-zeros more pressure.
HN feels mid-size in a good way. Most forums are a lot smaller, and then there are the few famous ones that are much much larger. There aren't that many in HN's order of magnitude. The mid range is a nice place to hang because although the problems are impossible, they're not utterly impossible. You can work with them around the margins.