In support of this—part of it!—here’s one paper of many: “The Neurobiology of Long COVID” by M. Monje, neurobiologist at Stanford, and A. Iwasaki, immunologist at Yale.
https://doi.org/10.1016/j.neuron.2022.10.006
People with measurable neurobiological issues will show a measurable productivity drop.
[1] https://jamanetwork.com/journals/jamanetworkopen/fullarticle...
Low cortisol is very common. That’s just one example. With low cortisol it’s hard to feel good or function 100%.
One paper of many that show this kind of relationship (a preprint): “Distinguishing features of Long COVID identified through immune profiling” — https://doi.org/10.1101/2022.08.09.22278592
It’s also important to note that there was a study that seemed to show that Long COVID was just anxiety or in people’s imagination. Because people who said they had Long COVID didn’t have SARS-CoV-2 antibodies. The thing is that not everybody seroconverts. Not everybody actually produces antibodies after infection; We simply can’t exclude Long COVID diagnoses based on looking at those particular antibodies. So that study can’t show what it has been said to show. (I can provide sources for this but am out of time. It’s on my honor.)
Either way, the treatment should be the same. Take a corticosteroid to lower the IL6 & 10 levels, ensure the patient is getting proper sleep and nutrients, and not doing anything to exacerbate lowered serotonin/dopamine levels, and cross your fingers.
I've started to hear of companies that are testing for elevated cytokines as a proof of long covid, and my family member's hospital has started educating their staff on cytokine release syndrome in the rare patient who has a reaction to a vaccine shot, both of which, for me, imply the industry might be moving in this direction for explanation. fingers crossed
60% of 160 million is 96 million. So 5% of that is 4.6 million people or so with at least a solid portion of a year of symptoms.
There's mounting evidence that some of the damage could take years to recover or even be lifelong.
The current word from the Mayo Clinic is about 20% of folks have what they're calling Post-COVID Syndrome between one month and one year after an infection, with at least one symptom likely from the viral infection. https://www.mayoclinic.org/diseases-conditions/coronavirus/i...
If we look at 20% of 60% of the workforce that's around 19 million people symptomatic for over a month after the initial positive test. Twelve percent, almost one in eight people in the workplace.
It’s a bit worse than a cold but much better for than the flu. So, yes, for us life just goes on with COVID. No need to change anything.
https://www.webmd.com/lung/news/20220707/each-covid-19-reinf...
Not necessarily worse, but there is cumulative damage.
In the UK, about 7% of COVID cases that get medical attention are now re-infections. That number increases with time; it was only 4% last February. Immunity from getting COVID is time-limited and not that long. One study said "time between reinfections ranged from 90 to 650 days, with the average being 343 days".
Over a decade, this might gradually debilitate most of the population.
Paper: Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection – https://doi.org/10.1038/s41590-021-01113-x
Paper: “Excess risk for acute myocardial infarction mortality during the COVID-19 pandemic” — https://doi.org/10.1002/jmv.28187
Paper: “p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)” — https://doi.org/10.3389/fphar.2022.871583
SARS-CoV-2 directly and indirectly interferes with p53 expression and balance.
On p53: “p53, cellular tumor antigen p53 (UniProt name); p53 proteins are crucial in vertebrates, where they prevent cancer formation. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. Hence TP53 is classified as a tumor suppressor gene.” — https://en.wikipedia.org/wiki/P53
The literature goes on and on and on. People really are not okay after contracting this virus. I know plenty of people who simply are not recovering after COVID illness. Friends. Close family. Kids.
We are being warned.
And crucially: We can clean this crap out of the air. Nobody has to breathe in SARS-CoV-2. We absolutely must demand that something is done. There’s lots and lots that can be done.
> We can clean this crap out of the air. Nobody has to breathe in SARS-CoV-2.
?? What do you even mean. Maybe if the vaccine prevented spreading the virus we could but until we develop that I don't see how that is possible.
Re. cleaning it out of the air: It’s literally airborne and it can literally be cleaned out of the air.
When infected, people emit tiny fluid particles which contain the virus. These are so small that they don’t fall to the ground. Filter materials like in HEPA filters and respirator masks strip these particles out of the air. Very effectively. (Surgical masks don’t work. Same kind of material, gaps at the sides. It doesn’t work.)
We can literally clean the air. We do not have to breathe this virus in. That’s just one of the things we can do.
Paper: “Effectiveness of HEPA Filters at Removing Infectious SARS-CoV-2 from the Air” – https://doi.org/10.1128/msphere.00086-22
Paper: “The Removal of Airborne Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Other Microbial Bioaerosols by Air Filtration on Coronavirus Disease 2019 (COVID-19) Surge Units” – https://doi.org/10.1093/cid/ciab933
“Ten scientific reasons in support of airborne transmission of SARS-CoV-2” – https://doi.org/10.1016/s0140-6736(21)00869-2
Why am I saying all of this?
Because I have a moral obligation to do so.
Why do I know this?
I don’t know anything. I’ve just read those scientific papers.
Why did I read them?
Because high-risk pregnancy.
But does it apply outside of high-risk pregnancy?
Yes.
It's shocking how much this can help with other things e.g. asthma or allergies.